I was born and brought up in a small town in central India. After doing my Undergrad and Masters at IIT Bombay, I worked as R&D Engineer at Central Transmission Utility of India (Powergrid Corp.) for 3 years. I joined University of Minnesota, Twin Cities as a PhD student in 2016. Here, I am part of Salapaka Lab (formerly known as Nano Dynamics Systems Laboratory). My research focus is on creating novel instruments and biochemical assays to investigate the mechanisms of intracellular transportation in eukaryotic cells. Outside academics, I am an amatuer Jazz drummer and like to watch sports, specially soccer.
PhD in Electrical Engineering • August 2016 - Present
Thesis: Regulation of intracellular transport by molecular motors: Theory, Instrumentation, and DNA based Single Molecule Techniques
Masters in Mathematics • August 2020 - Present
Thesis: Markov Chains Meet Molecular Motors
Master of Technology in Energy Systems Engineering • awarded on August 10th, 2013
Bachelor of Technology in Energy Science and Engineering • 2008-2013
Systems Engineering Intern • June 2019 - August 2019
Automated fault detection algorithms for next generation flow cytometers
R&D Engineer • August 2013 - August 2016
Design and Commissioning of world's highest voltage level (1200kV) electricity transmission station
Visiting Researcher at School of Engineering • June 2011 - July 2011
High-fidelity, continental scale renewable (solar + wind) energy systems models
Graduate School, UMN • 2021-22
Biophysical Society Meeting, San Francisco• 2022
Journal of Biological Chemistry • February 2022• Download pdf
ACS Biochemistry • November 2019• Download pdf
Journal of Social and Behavioral Sciences • August 2013 • Download pdf
Abstract published in ASCB 2017 Proceedings • December 2017• Download pdf
Throughout my academic career, I have aimed to develop a rigorous mathematical understanding of the techniques I am using to solve any systems level problem. I have taken several math courses on analysis and stochastic processes to accurately model the systems I am working with and work with guarantees. I apply the knowledge gained through my academic course and solve Kolmogorov's master equations to understand the nature of intracellular transportation.
Investigation of principles of transportation of material that takes place inside a cell and study of the macro-level effects of disruption of transport on micro-level. This project is in collaboration with Prof. Tom Hays, Molecular and Cell Biology at University of Minnesota
Modeling, Simulation, Single Molecule ExperimentationWe create customized instruments such as Optical Tweezer, Atomic Force Microscope and Total Internal Reflection Fluorescence (TIRF) Microscope. These are tools to investigate physics and biology at nanometer scale resolution.
Instrumentation, Optical Tweezers, TIRF MicroscopyWe use novel machine learning techniques on primate brain neural spiking data from pre-frontal cortex (PFC) region to better understand working of brain. Such studies are helpful in creating better brain-computer interfaces.
Neuroscience, Machine Learning, Pre-frontal Cortex, BCI• Our work on role of cargo-motor interaction kinetics during multi-motor intracellular cargo transport has been recognized with Student Research Achievement Award (SRAA) at 2022 Annual Biophyisical Society Meeting held at San Francisco, CA
• I have been awarded Graduate School's prestegious Doctoral Dissertation Fellowship for academic year 2021-22. I thank the committee to recognize the efforts our team has put into achieving our research goals.
• Our study titled "Stiffness of cargo–motor linkage tunes myosin VI motility and response to load" has been selected as the cover article for November 2019 issue of ACS Biochemistry journal.
• I delieverd a talk on our study about the role of linkage stiffness during intracellular cargo transport at 2022 American Physical Society March meeting.
• I recently presented a poster in ASCB 2017 held in Philadelphia PA. The title of the poster was "Bi-Directional Transport Properties of 2-Species Molecular Motor Ensemble" The details of this work can be found in "Research" section.
If you have a question regarding my work, or want to discuss potential research projects on which we can collaborate, feel free to give me a shout below. I usually reply within 1-2 days.